Introduction to T-cell Receptors and Repertoires

Leon Eyrich Jessen

2026

Role of T-cell Receptor in Immune Activation

Neefjes, J., Jongsma, M., Paul, P. et al. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat Rev Immunol 11, 823–836 (2011). https://doi.org/10.1038/nri3084

Generation of TCR Diversity by Somatic Recombination of Gene Segments

Gene segments: 43 Vα, 58 Jα and 42 Vβ, 2 Dβ, 12 Jβ

Turner, S., Doherty, P., McCluskey, J. et al. Structural determinants of T-cell receptor bias in immunity. Nat Rev Immunol 6, 883–894 (2006). https://doi.org/10.1038/nri1977

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