Static outliers for Healthier Lancashire And South Cumbria

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Healthier Lancashire And South Cumbria is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Secukinumab 1 Rheumatic disease suppressant drugs 44081 0.00 0.0 0.00 6.33
Salicylic acid 11 Drugs for oral ulceration and inflammation 5164 0.00 0.0 0.00 4.86
Nadolol 803 Beta-adrenoceptor blocking drugs 654716 0.00 0.0 0.00 4.77
Levocetirizine 3200 Antihistamines 183434 0.02 0.0 0.00 4.36
Triamcinolone hexacetonide 423 Local corticosteroid injections 10861 0.04 0.0 0.01 4.05

Prescribing where Healthier Lancashire And South Cumbria is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Prucalopride 1325 Other drugs used in constipation 2725 0.49 0.75 0.10 -2.65
Mercaptopurine 594 Antimetabolites 2031 0.29 0.75 0.23 -1.96
Nicotine 1522 Nicotine dependence 4447 0.34 0.60 0.14 -1.83
Nicotine 500micrograms/dose nasal spray : 7
Nicotine 7mg/24hours transdermal patches : 50
Nicotine 14mg/24hours transdermal patches : 125
Nicotine 21mg/24hours transdermal patches : 288
Nicotine 10mg/16hours transdermal patches : 44
Nicotine 15mg/16hours transdermal patches : 125
Nicotine 2mg sublingual tablets sugar free : 2
Nicotine 2mg lozenges sugar free : 42
Nicotine 4mg lozenges sugar free : 46
Nicotine 2mg medicated chewing gum sugar free : 43
Nicotine 4mg medicated chewing gum sugar free : 36
Nicotine 1.5mg lozenges sugar free : 1
Nicotine 25mg/16hours transdermal patches : 138
Nicotine 1mg/dose oromucosal spray sugar free : 77
Nicotine 15mg inhalation cartridges with device : 169
Nicorette 500micrograms/dose nasal spray : 5
Nicorette Freshmint 4mg medicated chewing gum : 1
Nicorette Fruitfusion 2mg medicated chewing gum : 4
Nicorette Fruitfusion 4mg medicated chewing gum : 2
Nicorette invisi 10mg/16hours patches : 13
Nicorette invisi 15mg/16hours patches : 19
Nicorette invisi 25mg/16hours patches : 45
Nicorette Icy White 2mg medicated chewing gum : 4
Nicorette Icy White 4mg medicated chewing gum : 16
Nicorette QuickMist 1mg/dose mouthspray freshmint : 99
Nicorette 15mg Inhalator : 53
Nicorette Cools 2mg lozenges : 3
Nicorette Cools 4mg lozenges : 1
Nicorette QuickMist 1mg/dose mouthspray cool berry : 11
Nicotinell TTS 20 patches : 3
Nicotinell TTS 30 patches : 10
Nicotinell Mint 2mg medicated chewing gum : 1
Nicotinell Fruit 2mg medicated chewing gum : 1
Nicotinell Fruit 4mg medicated chewing gum : 3
NiQuitin 21mg patches : 2
NiQuitin Clear 21mg patches : 10
NiQuitin Clear 14mg patches : 2
NiQuitin Clear 7mg patches : 1
NiQuitin Mint 4mg lozenges : 3
NiQuitin Minis Mint 4mg lozenges : 10
NiQuitin Minis Mint 1.5mg lozenges : 7
Fosfomycin trometamol 147 Some other antibacterials 2210 0.07 0.41 0.19 -1.80
Salbutamol 310025 Selective beta(2)-agonists 360644 0.86 0.90 0.02 -1.78
Salbutamol 100micrograms/dose inhaler CFC free : 237115
Salbutamol 200micrograms/dose dry powder inhaler : 2299
Salbutamol 2.5mg/2.5ml nebuliser liquid unit dose vials : 4795
Salbutamol 2mg tablets : 27
Salbutamol 4mg tablets : 5
Salbutamol 5mg/ml nebuliser liquid : 1
Salbutamol 5mg/2.5ml nebuliser liquid unit dose vials : 2639
Salbutamol 2mg/5ml oral solution sugar free : 65
Salbutamol 100micrograms/dose breath actuated inh CFC free : 15956
Salbutamol 100micrograms/dose dry powder inhaler : 698
Salbutamol 100microg/dose dry pdr inhalation cart with dev : 7
Salbutamol 100micrograms/dose dry pdr inhalation cartridge : 7
Ventolin 200micrograms/dose Accuhaler : 2973
Ventolin 100micrograms/dose Evohaler : 28558
Ventolin 2mg/5ml syrup : 3
Ventolin 2.5mg Nebules : 216
Ventolin 5mg/5ml solution for infusion ampoules : 1
Ventolin 5mg Nebules : 213
Salamol 100micrograms/dose inhaler CFC free (Teva) : 2069
Salamol 100micrograms/dose Easi-Breathe inhaler : 4976
Airomir 100micrograms/dose inhaler : 41
Airomir 100micrograms/dose Autohaler : 747
Easyhaler Salbutamol sulfate 100micrograms/dose dry pdr inh : 5674
Easyhaler Salbutamol sulfate 200micrograms/dose dry pdr inh : 937
Salbulin Novolizer 100micrograms/dose inhalation powder : 3