Static outliers for Hawthorn Mc

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Hawthorn Mc is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Disopyramide phosphate 3 Drugs for arrhythmias 6 0.50 0.00 0.03 17.95
Dextromethorphan hydrobromide 2 Cough suppressants 2 1.00 0.01 0.06 15.89
Azilsartan medoxomil 2 Angiotensin-II receptor antagonists 471 0.00 0.00 0.00 11.47
Ergocalciferol 33 Vitamin D 489 0.07 0.00 0.01 10.26
Disopyramide 3 Drugs for arrhythmias 6 0.50 0.02 0.06 7.60

Prescribing where Hawthorn Mc is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Colecalciferol 440 Vitamin D 489 0.90 0.96 0.02 -2.56
Colecalciferol 800unit capsules : 33
Colecalciferol 400unit tablets : 40
Adcal-D3 chewable tablets tutti frutti : 54
Adcal-D3 750mg/200unit caplets : 51
Calcichew D3 Forte chewable tablets : 38
Hux D3 20,000unit capsules : 89
Colecalciferol 1,000unit tablets : 2
Colecalciferol 2,000units/ml oral drops sugar free : 2
Colecalciferol 20,000unit tablets : 2
Colecalciferol 20,000unit capsules : 2
Colecalciferol 200units/drop oral drops : 2
Colecalciferol 1,000unit capsules : 1
Colecalciferol 2,740units/ml oral drops sugar free : 1
Colecalciferol 50,000unit capsules : 1
SunVit-D3 10,000unit tablets : 1
SunVit-D3 400unit tablets : 1
Fultium-D3 800unit capsules : 1
Thorens 25,000units/2.5ml oral solution : 1
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 28
Colecalciferol 800unit tablets : 9
Thorens 10,000units/ml oral drops : 4
Calceos 500mg/400unit chewable tablets : 13
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 12
Cacit D3 effervescent granules sachets : 6
Desunin 800unit tablets : 6
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 20
Colecalciferol 400unit capsules : 10
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 5
Fultium-D3 2,740units/ml oral drops : 5
Methotrexate 17 Rheumatic disease suppressant drugs 74 0.23 0.58 0.15 -2.26
Simvastatin 102 Lipid-regulating drugs 1870 0.05 0.22 0.08 -2.21
Codeine phosphate 0 Cough suppressants 2 0.00 0.76 0.35 -2.18
Donepezil hydrochloride 4 Drugs for dementia 36 0.11 0.49 0.19 -2.05