Static outliers for Shakespeare Medical Practice

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Shakespeare Medical Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Calcitriol 27 Vitamin D 395 0.07 0.00 0.00 16.70
Maltodextrin 8 Foods for special diets 26 0.31 0.01 0.02 12.83
Testosterone enantate 2 Male sex hormones and antagonists 24 0.08 0.00 0.01 12.73
Fosinopril sodium 2 Angiotensin-converting enzyme inhibitors 555 0.00 0.00 0.00 7.50
Haloperidol 54 Antipsychotic drugs 221 0.24 0.03 0.03 7.17

Prescribing where Shakespeare Medical Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Allopurinol 82 Gout and cytotoxic induced hyperiuicaemia 120 0.68 0.89 0.05 -3.96
Methylphenidate hydrochloride 0 CNS Stimulants and drugs used for ADHD 14 0.00 0.65 0.21 -3.15
Azathioprine 7 Antiproliferative immunosuppressants 22 0.32 0.80 0.19 -2.62
Colecalciferol 356 Vitamin D 395 0.90 0.96 0.02 -2.50
Colecalciferol 800unit capsules : 60
Calceos 500mg/400unit chewable tablets : 46
Calci-D 1000mg/1,000unit chewable tablets : 66
Colecalciferol 2,400units/ml oral drops sugar free : 2
Hux D3 20,000unit capsules : 2
Desunin 800unit tablets : 2
Thorens 10,000units/ml oral drops : 2
Colecalciferol 25,000unit tablets : 1
Colecalciferol 400units/ml oral drops sugar free : 1
SunVit-D3 20,000unit tablets : 1
Colecalciferol 20,000unit capsules : 14
Accrete D3 tablets : 9
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 4
Adcal-D3 750mg/200unit caplets : 4
InVita D3 50,000units/1ml oral solution : 4
Colecalciferol 1,000unit capsules : 8
Colecalciferol 50,000unit capsules : 3
Adcal-D3 Lemon chewable tablets : 3
SunVit-D3 800unit tablets : 3
InVita D3 25,000units/1ml oral solution : 3
Colecalciferol 20,000unit tablets : 21
Colecalciferol 1,000unit tablets : 11
Colecalciferol 400unit tablets : 11
Fultium-D3 800unit capsules : 6
Adcal-D3 chewable tablets tutti frutti : 20
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 24
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 5
Colecalciferol 25,000units/1ml soln ud amp sugar free : 5
Colecalciferol 10,000units/ml oral drops sugar free : 5
Colecalciferol 1,000unit / Calcium carbonate 2.5g chew tab : 5
Stexerol-D3 1,000unit tablets : 5
Finasteride 13 Male sex hormones and antagonists 24 0.54 0.82 0.12 -2.41