Static outliers for The Orchard Surgery

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where The Orchard Surgery is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Empagliflozin/metformin 183 Other antidiabetic drugs 777 0.24 0.00 0.02 12.29
Phenoxybenzamine hydrochloride 2 Alpha-adrenoceptor blocking drugs 198 0.01 0.00 0.00 10.68
Torasemide 10 Loop diuretics 395 0.03 0.00 0.00 5.05
Levobunolol hydrochloride 6 Treatment of glaucoma 325 0.02 0.00 0.00 4.97
Rotigotine 15 Dopaminergic drugs used in parkinsonism 80 0.19 0.03 0.04 3.99

Prescribing where The Orchard Surgery is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Colecalciferol 559 Vitamin D 637 0.88 0.96 0.02 -3.46
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 35
Colecalciferol 20,000unit capsules : 208
Accrete D3 tablets : 72
Adcal-D3 chewable tablets tutti frutti : 50
Adcal-D3 Lemon chewable tablets : 29
Adcal-D3 750mg/200unit caplets : 45
Colecalciferol 1,000unit tablets : 2
Colecalciferol 880unit / Calcium carbonate 2.5g chew tab : 2
InVita D3 25,000units/1ml oral solution : 2
Colecalciferol 600unit capsules : 1
Colecalciferol 400unit capsules : 1
Colecalciferol 5,000unit capsules : 1
Colecalciferol 400unit tablets : 1
SunVit-D3 10,000unit capsules : 1
Plenachol D3 20,000unit capsules : 1
Accrete D3 One a Day 1000mg/880unit chewable tablets : 9
Calcichew D3 chewable tablets : 4
Colecalciferol 800unit capsules : 27
Colecalciferol 25,000units/1ml soln ud amp sugar free : 8
Calceos 500mg/400unit chewable tablets : 8
Calcichew D3 Forte chewable tablets : 8
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 3
Colecalciferol 2,740units/ml oral drops sugar free : 3
Fultium-D3 800unit capsules : 16
OsteoCaps D3 20,000unit capsules : 11
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 6
Natecal D3 600mg/400unit chewable tablets : 5
Aciclovir 17 Herpes simplex and varicella-zoster 23 0.74 0.95 0.07 -3.13
Theophylline 3 Theophylline 13 0.23 0.83 0.25 -2.44
Sodium cromoglicate 13 Other anti-inflammatory preparations 58 0.22 0.67 0.18 -2.43
Mercaptopurine 0 Antimetabolites 4 0.00 0.80 0.35 -2.31