Static outliers for Modality Enki Medical Practice

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Modality Enki Medical Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Etanercept 1 Rheumatic disease suppressant drugs 391 0.00 0.00 0.00 61.94
Adalimumab 1 Rheumatic disease suppressant drugs 391 0.00 0.00 0.00 27.26
Baricitinib 2 Rheumatic disease suppressant drugs 391 0.01 0.00 0.00 16.97
Dexamfetamine sulfate 10 CNS Stimulants and drugs used for ADHD 17 0.59 0.03 0.07 8.51
Isotretinoin 4 Oral preparations for acne 4 1.00 0.03 0.13 7.22

Prescribing where Modality Enki Medical Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 0 Oral preparations for acne 4 0.00 0.97 0.13 -7.22
Colecalciferol 1050 Vitamin D 1204 0.87 0.96 0.02 -3.68
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 80
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 60
Accrete D3 tablets : 138
Adcal-D3 chewable tablets tutti frutti : 143
Adcal-D3 750mg/200unit caplets : 175
Fultium-D3 20,000unit capsules : 53
Hux D3 20,000unit capsules : 63
InVita D3 50,000unit capsules : 109
Colecalciferol 20,000unit tablets : 2
Colecalciferol 800unit / Calcium carbonate 2.5g chewable tab : 2
Colecalciferol 10,000units/ml oral solution sugar free : 2
InVita D3 800unit capsules : 2
Colecalciferol 200unit / Calcium carbonate 1.25g chew tab : 1
Colecalciferol 400unit / Calcium carbonate 1.25g tablets : 1
Colecalciferol 400unit tablets : 1
Pro D3 400unit capsules : 1
Pro D3 forte 3,000units/ml liquid : 1
Evacal D3 1500mg/400unit chewable tablets : 1
InVita D3 400unit capsules : 1
InVita D3 50,000units/1ml oral solution : 14
Adcal-D3 Lemon chewable tablets : 28
InVita D3 25,000unit capsules : 9
Calcichew D3 Forte chewable tablets : 23
Colecalciferol 20,000unit capsules : 4
Fultium-D3 3,200unit capsules : 4
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 18
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 8
Colecalciferol 1,000unit tablets : 22
Colecalciferol 25,000units/1ml soln ud amp sugar free : 3
Calceos 500mg/400unit chewable tablets : 3
Fultium-D3 2,740units/ml oral drops : 3
Colecalciferol 800unit capsules : 17
Calcichew D3 chewable tablets : 7
Colecalciferol 400unit / Calcium carbonate 1.5g tablets : 6
Colecalciferol 800unit tablets : 6
Colecalciferol 1,000unit capsules : 5
Calfovit D3 oral powder sachets : 5
InVita D3 25,000units/1ml oral solution : 5
Thorens 10,000units/ml oral drops : 5
Fultium-D3 800unit capsules : 19
Methylphenidate hydrochloride 0 CNS Stimulants and drugs used for ADHD 17 0.00 0.65 0.21 -3.15
Water for injection 0 Electrolytes and water 2 0.00 0.82 0.26 -3.14
Medroxyprogesterone acetate 23 Parenteral progestogen-only contraceptives 61 0.38 0.88 0.16 -3.10