Static outliers for Alpha Medical Practice

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Alpha Medical Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Pantoprazole 1007 Proton pump inhibitors 2362 0.43 0.02 0.02 18.31
Bifonazole 1 Antifungal preparations 60 0.02 0.00 0.00 14.11
Linagliptin/metformin 216 Other antidiabetic drugs 1701 0.13 0.00 0.01 9.42
Heparin flushes 1 Parenteral anticoagulants 1 1.00 0.04 0.13 7.30
Rotigotine 6 Dopaminergic drugs used in parkinsonism 19 0.32 0.03 0.04 7.25

Prescribing where Alpha Medical Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Colecalciferol 690 Vitamin D 786 0.88 0.96 0.02 -3.44
Adcal-D3 750mg/200unit caplets : 146
Fultium-D3 800unit capsules : 31
Hux D3 20,000unit capsules : 331
InVita D3 800unit capsules : 47
Fultium-D3 3,200unit capsules : 2
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 1
Colecalciferol 50,000unit tablets : 1
Colecalciferol 25,000unit tablets : 1
Colecalciferol 20,000unit capsules : 1
Colecalciferol 10,000unit capsules : 1
SunVit-D3 20,000unit tablets : 1
SunVit-D3 50,000unit tablets : 1
SunVit-D3 2,000units/ml oral solution : 1
Desunin 800unit tablets : 1
InVita D3 25,000units/1ml oral solution : 1
InVita D3 50,000units/1ml oral solution : 1
Stexerol-D3 25,000unit tablets : 1
Calcichew D3 chewable tablets : 4
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 8
SunVit-D3 1,000unit tablets : 8
Adcal-D3 chewable tablets tutti frutti : 12
Colecalciferol 800unit capsules : 6
Colecalciferol 1,000unit capsules : 6
Colecalciferol 800unit tablets : 6
Calcichew D3 500mg/400unit caplets : 6
TheiCal-D3 1000mg/880unit chewable tablets : 6
Aciferol D3 2,000units/ml liquid : 15
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 24
Colecalciferol 400unit tablets : 5
Colecalciferol 50,000unit capsules : 5
SunVit-D3 2,000units/ml oral drops : 5
Calci-D 1000mg/1,000unit chewable tablets : 5
Bendroflumethiazide 47 Thiazides and related diuretics 305 0.15 0.58 0.16 -2.67
Mebeverine hydrochloride 17 Antispasmodic and other drugs altering gut motility 136 0.12 0.45 0.13 -2.56
Calcium carbonate 11 Calcium supplements 18 0.61 0.95 0.13 -2.55
Mercaptopurine 0 Antimetabolites 6 0.00 0.80 0.35 -2.31