Static outliers for Mill Stream Surgery

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Mill Stream Surgery is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Doxepin hydrochloride 3 Topical local anaesthetics and antipruritics 6 0.50 0.01 0.05 8.99
Cholera 1 Vaccines and antisera 21 0.05 0.00 0.01 7.66
Liothyronine sodium 12 Thyroid hormones 767 0.02 0.00 0.00 5.01
Denosumab 30 Bisphosphonates and other drugs 290 0.10 0.01 0.02 4.98
Liraglutide 22 Other antidiabetic drugs 135 0.16 0.03 0.03 4.67

Prescribing where Mill Stream Surgery is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Levothyroxine sodium 755 Thyroid hormones 767 0.98 1.00 0.00 -4.84
Acamprosate calcium 0 Alcohol dependence 5 0.00 0.83 0.31 -2.70
Azathioprine 5 Antiproliferative immunosuppressants 16 0.31 0.80 0.19 -2.65
Alginic acid compound preparations 76 Compound Alginates and proprietary indigestion preparations 79 0.96 1.00 0.01 -2.56
Glucose blood testing reagents 171 Diabetic diagnostic and monitoring agents 199 0.86 0.95 0.03 -2.54