Static outliers for Central Medical Centre

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Central Medical Centre is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Glycopyrronium/formoterol 4 Compound bronchodilator preparations 35 0.11 0.00 0.01 18.14
Tropicamide 1 Mydriatics and cycloplegics 1 1.00 0.02 0.12 8.44
Heparin flushes 1 Parenteral anticoagulants 1 1.00 0.04 0.13 7.30
Aprepitant 1 Drugs used in nausea and vertigo 234 0.00 0.00 0.00 7.04
Heparinoid 150 Rubefacients, topical NSAIDS, capsaicin and poultice 542 0.28 0.03 0.05 5.42

Prescribing where Central Medical Centre is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Colecalciferol 1240 Vitamin D 1375 0.90 0.96 0.02 -2.48
Colecalciferol 1,000unit tablets : 159
Colecalciferol 200unit / Calcium carbonate 1.25g chew tab : 59
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 53
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 171
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 34
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 37
Colecalciferol 800unit tablets : 63
Colecalciferol 20,000unit capsules : 44
Accrete D3 tablets : 110
Valupak Vitamin D3 1,000unit tablets : 133
Adcal-D3 chewable tablets tutti frutti : 62
Adcal-D3 750mg/200unit caplets : 77
Evacal D3 1500mg/400unit chewable tablets : 69
Colecalciferol 2,000units/ml oral drops sugar free : 2
Colecalciferol 10,000unit tablets : 2
Colecalciferol 5,000unit capsules : 2
Pro D3 1,000unit capsules : 2
SunVit-D3 20,000unit tablets : 2
Fultium-D3 3,200unit capsules : 2
Colecalciferol 400unit capsules : 1
Colecalciferol 400units/dose oral spray sugar free : 1
Colecalciferol 200units/drop oral drops sugar free : 1
Colecalciferol 2,000unit orodispersible tablets sugar free : 1
Calcichew D3 Forte chewable tablets : 1
SunVit-D3 1,000unit tablets : 1
SunVit-D3 20,000unit capsules : 1
Strivit-D3 20,000unit capsules : 1
Colecalciferol 400unit tablets : 4
Colecalciferol 400unit / Calcium carbonate 1.5g tablets : 8
Calcichew D3 chewable tablets : 8
Colecalciferol 1,000unit capsules : 3
Colecalciferol 440unit/Calcium carb 1.25g efferv gran sach : 3
Colecalciferol 800unit capsules : 17
Colecalciferol 4,000unit tablets : 12
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 7
Fultium-D3 800unit capsules : 7
Adcal-D3 Lemon chewable tablets : 11
Calceos 500mg/400unit chewable tablets : 20
Colecalciferol 20,000unit tablets : 15
Stexerol-D3 1,000unit tablets : 10
Colecalciferol 3,200unit capsules : 5
Hux D3 20,000unit capsules : 19
Urea hydrogen peroxide 0 Removal of ear wax and other substances 1 0.00 0.83 0.34 -2.47
Furosemide 534 Loop diuretics 820 0.65 0.86 0.09 -2.29
Clopidogrel 403 Antiplatelet drugs 2084 0.19 0.32 0.06 -2.04
Latanoprost 43 Treatment of glaucoma 313 0.14 0.31 0.08 -2.04