Static outliers for The Green & Fir Road

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where The Green & Fir Road is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Erythromycin stearate 18 Macrolides 111 0.16 0.00 0.01 17.78
Hydrogen peroxide 5 Mouth-washes, gargles and dentifrices 8 0.62 0.01 0.05 11.59
Gemfibrozil 9 Lipid-regulating drugs 3413 0.00 0.00 0.00 7.11
Other oral iron preparations 8 Oral iron 182 0.04 0.00 0.01 6.63
Estradiol valandestradiol valerate with dienogest 6 Combined hormonal contraceptives 192 0.03 0.00 0.01 5.50

Prescribing where The Green & Fir Road is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Chlorhexidine gluconate 3 Mouth-washes, gargles and dentifrices 8 0.38 0.97 0.11 -5.69
Aciclovir 45 Herpes simplex and varicella-zoster 62 0.73 0.95 0.07 -3.32
Spironolactone 75 Potassium-sparing diuretics and aldosterone antagonists 221 0.34 0.72 0.14 -2.77
Colecalciferol 655 Vitamin D 729 0.90 0.96 0.02 -2.61
Colecalciferol 800unit capsules : 43
Colecalciferol 1,000unit capsules : 37
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 117
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 69
Adcal-D3 750mg/200unit caplets : 84
Calcichew D3 Forte chewable tablets : 89
Strivit-D3 20,000unit capsules : 30
Colecalciferol 2,000unit tablets : 2
Accrete D3 One a Day 1000mg/880unit chewable tablets : 2
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 2
Colecalciferol 600unit capsules : 1
Colecalciferol 2,000units/ml oral drops sugar free : 1
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 1
Colecalciferol 3,200unit capsules : 1
Colecalciferol 10,000unit capsules : 1
Colecalciferol 3,000unit capsules : 1
Colecalciferol 200units/drop oral drops : 1
Calcichew D3 1000mg/800unit Once Daily chewable tablets : 1
SunVit-D3 10,000unit capsules : 1
Fultium-D3 3,200unit capsules : 1
Fultium-D3 2,740units/ml oral drops : 1
Thorens 10,000units/ml oral drops : 1
ColeDose D3 20,000unit capsules : 1
Adcal-D3 chewable tablets tutti frutti : 14
Colecalciferol 400unit / Calcium carbonate 1.5g tablets : 9
Colecalciferol 5,000units/5ml oral solution : 4
Colecalciferol 800unit / Calcium carbonate 2.5g chewable tab : 4
Colecalciferol 4,000unit capsules : 4
Accrete D3 tablets : 4
Colecalciferol 40,000unit capsules : 8
Colecalciferol 20,000unit capsules : 3
Solgar Vitamin D3 1,000unit capsules : 3
Colecalciferol 400unit capsules : 7
Plenachol D3 40,000unit capsules : 16
Fultium-D3 20,000unit capsules : 11
Colecalciferol 1,000unit tablets : 6
Desunin 800unit tablets : 6
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 20
Colecalciferol 2,000unit capsules : 10
Adcal-D3 Lemon chewable tablets : 19
Stexerol-D3 1,000unit tablets : 19
Moxonidine 0 Centrally-acting antihypertensive drugs 1 0.00 0.64 0.34 -1.92