Static outliers for Rainbow Practice

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Rainbow Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Co-phenotrope (Diphenox hydrochloride/atropine sulfate) 5 Antimotility drugs 38 0.13 0.00 0.00 26.81
Ranitidine hydrochloride 6 H2-Receptor antagonists 6 1.00 0.04 0.12 8.22
Sterculia 8 Bulk-forming laxatives 15 0.53 0.04 0.07 6.78
Amiloride hydrochloride with loop diuretics 16 Potassium sparing diuretics and compounds 28 0.57 0.02 0.08 6.75
Dithranol 4 Preparations for psoriasis 57 0.07 0.00 0.01 6.48

Prescribing where Rainbow Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Loperamide hydrochloride 33 Antimotility drugs 38 0.87 1.00 0.01 -11.04
Ispaghula husk 7 Bulk-forming laxatives 15 0.47 0.96 0.07 -6.71
Famotidine 0 H2-Receptor antagonists 6 0.00 0.78 0.23 -3.34
Cabergoline 0 Bromocriptine and other dopaminergic drugs 1 0.00 0.86 0.27 -3.16
Colecalciferol 1042 Vitamin D 1161 0.90 0.96 0.02 -2.65
Colecalciferol 1,000unit tablets : 32
Colecalciferol 1,000unit capsules : 35
Colecalciferol 200unit / Calcium carbonate 1.25g chew tab : 44
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 93
Colecalciferol 20,000unit capsules : 42
Accrete D3 tablets : 114
Valupak Vitamin D3 1,000unit tablets : 37
Adcal-D3 chewable tablets tutti frutti : 61
Adcal-D3 750mg/200unit caplets : 53
Calceos 500mg/400unit chewable tablets : 72
Calcichew D3 Forte chewable tablets : 75
Hux D3 20,000unit capsules : 152
Evacal D3 1500mg/400unit chewable tablets : 61
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 2
Solgar Vitamin D3 2,200unit capsules : 2
Bio-Vitamin D3 800unit capsules : 2
Colecalciferol 400unit capsules : 1
Colecalciferol 400unit / Calcium carbonate 1.5g tablets : 1
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 1
Colecalciferol 5,000unit tablets : 1
Colecalciferol 400units/ml oral drops sugar free : 1
Solgar Vitamin D3 1,000unit capsules : 1
Colecalciferol 600unit capsules : 14
Accrete D3 One a Day 1000mg/880unit chewable tablets : 9
Colecalciferol 2,000units/ml oral drops sugar free : 23
Colecalciferol 2,000unit tablets : 4
OsteoCaps D3 1,000unit capsules : 4
HealthAid Vitamin D3 200units/drop oral drops : 4
Fultium-D3 800unit capsules : 3
Calcichew D3 chewable tablets : 12
Colecalciferol 2,400units/ml oral drops sugar free : 7
Pro D3 2,000units/ml liquid drops : 7
Colecalciferol 2,500unit capsules : 6
Calcichew D3 1000mg/800unit Once Daily chewable tablets : 6
Stexerol-D3 25,000unit tablets : 6
Colecalciferol 3,000unit tablets : 5
Colecalciferol 800unit tablets : 5
Pro D3 20,000unit capsules : 5
Adcal-D3 Lemon chewable tablets : 5
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 5
Bio-Vitamin D3 1,000unit capsules : 5
Stexerol-D3 1,000unit tablets : 5
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 19