Static outliers for Chowdhury

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Chowdhury is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Cefuroxime axetil 57 Cephalosporins 176 0.32 0.00 0.03 11.37
Paroxetine hydrochloride 204 Selective serotonin re-uptake inhibitors 954 0.21 0.03 0.02 9.99
Amantadine hydrochloride 36 Dopaminergic drugs used in parkinsonism 82 0.44 0.03 0.04 9.69
Triamcinolone hexacetonide 1 Local corticosteroid injections 3 0.33 0.00 0.03 9.55
Miconazole nitrate 4 Vaginal and vulval infections 12 0.33 0.01 0.04 8.87

Prescribing where Chowdhury is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Desogestrel 20 Oral progestogen-only contraceptives 36 0.56 0.94 0.05 -7.05
Clotrimazole 5 Vaginal and vulval infections 12 0.42 0.90 0.10 -5.02
Colecalciferol 486 Vitamin D 574 0.85 0.96 0.02 -4.70
Colecalciferol 800unit capsules : 63
Colecalciferol 880unit / Calcium carbonate 2.5g chew tab : 103
Adcal-D3 chewable tablets tutti frutti : 118
InVita D3 800unit capsules : 42
Calci-D 1000mg/1,000unit chewable tablets : 90
Calcichew D3 Forte chewable tablets : 2
Desunin 800unit tablets : 2
Stexerol-D3 1,000unit tablets : 2
Colecalciferol 1,000unit tablets : 1
Colecalciferol 200unit / Calcium carbonate 1.25g chew tab : 1
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 1
Colecalciferol 800unit/Calcium phosphate 3.1g oral pdr sach : 1
Adcal-D3 750mg/200unit caplets : 1
Calceos 500mg/400unit chewable tablets : 1
Cacit D3 effervescent granules sachets : 4
Fultium-D3 800unit capsules : 4
Colecalciferol 800unit tablets : 12
Colecalciferol 1,000unit capsules : 11
Hux D3 20,000unit capsules : 6
TheiCal-D3 1000mg/880unit chewable tablets : 6
Colecalciferol 800unit / Calcium carbonate 2.5g chewable tab : 15
Glucose 0 Treatment of hypoglycaemia 1 0.00 0.75 0.21 -3.62
Cefalexin 119 Cephalosporins 176 0.68 0.96 0.10 -2.77