Static outliers for The Enterprise Practice

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where The Enterprise Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Rupatadine fumarate 7 Antihistamines 403 0.02 0.00 0.00 19.67
Minoxidil 6 Shampoos and some other scalp preparations 37 0.16 0.00 0.01 13.39
Perindopril arginine 14 Angiotensin-converting enzyme inhibitors 703 0.02 0.00 0.00 9.44
Doxepin 5 Tricyclic and related antidepressant drugs 173 0.03 0.00 0.00 6.99
Etonogestrel 1 Parenteral progestogen-only contraceptives 1 1.00 0.12 0.16 5.42

Prescribing where The Enterprise Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Medroxyprogesterone acetate 0 Parenteral progestogen-only contraceptives 1 0.00 0.88 0.16 -5.42
Trimethoprim 4 Sulfonamides and trimethoprim 14 0.29 0.86 0.13 -4.48
Colecalciferol 444 Vitamin D 497 0.89 0.96 0.02 -2.82
Calcichew D3 Forte chewable tablets : 42
Fultium-D3 20,000unit capsules : 36
Evacal D3 1500mg/400unit chewable tablets : 146
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 2
Colecalciferol 400unit tablets : 2
Stexerol-D3 1,000unit tablets : 2
Colecalciferol 20,000unit tablets : 1
Colecalciferol 800unit tablets : 1
Colecalciferol 40,000unit capsules : 1
Colecalciferol 4,000unit tablets : 1
Adcal-D3 Lemon chewable tablets : 1
Calcichew D3 chewable tablets : 1
Calci-D 1000mg/1,000unit chewable tablets : 1
Fultium-D3 800unit capsules : 14
Colecalciferol 400unit / Calcium carbonate 1.5g tablets : 9
Calceos 500mg/400unit chewable tablets : 4
Calcichew D3 1000mg/800unit Once Daily chewable tablets : 4
Fultium-D3 3,200unit capsules : 4
Hux D3 20,000unit capsules : 4
Colecalciferol 800unit capsules : 13
Colecalciferol 1,000unit capsules : 8
Colecalciferol 400unit / Calcium carbonate 1.25g chew tab : 8
Colecalciferol 20,000unit capsules : 3
Colecalciferol 2,500unit capsules : 3
Adcal-D3 750mg/200unit caplets : 3
SunVit-D3 10,000unit tablets : 3
InVita D3 25,000units/1ml oral solution : 3
Stexerol-D3 25,000unit tablets : 3
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 12
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 26
Colecalciferol 1,000unit tablets : 21
Adcal-D3 chewable tablets tutti frutti : 25
Valupak Vitamin D3 1,000unit tablets : 6
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 6
Accrete D3 tablets : 15
Colecalciferol 440unit/Calcium carb 1.25g efferv gran sach : 5
Colecalciferol 1,000unit / Calcium carbonate 2.5g chew tab : 5
Fluconazole 9 Triazole antifungals 16 0.56 0.85 0.15 -1.96
Procyclidine hydrochloride 5 Antimuscarinic drugs used in parkinsonism 11 0.45 0.84 0.21 -1.86