Static outliers for Spectrum Health

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Spectrum Health is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Perphenazine 2 Antipsychotic drugs 276 0.01 0.00 0.00 33.57
Dexketoprofen 5 Non-steroidal anti-inflammatory drugs 372 0.01 0.00 0.00 21.16
Spironolactone with loop diuretics 4 Potassium sparing diuretics and compounds 4 1.00 0.01 0.08 12.90
Other lozenge and spray preparations 1 Lozenges and sprays 1 1.00 0.01 0.08 11.73
Azithromycin 3 Antibacterials 28 0.11 0.00 0.01 11.64

Prescribing where Spectrum Health is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Potassium citrate 0 Drugs used in urological pain 1 0.00 0.93 0.24 -3.87
Other multivitamin preparations 2 Multivitamin preparations 8 0.25 0.81 0.21 -2.69
Colecalciferol 849 Vitamin D 936 0.91 0.96 0.02 -2.27
Colecalciferol 400unit / Calcium carbonate 1.5g chewable tab : 34
Colecalciferol 200unit / Calcium carbonate 750mg tablets : 89
Adcal-D3 chewable tablets tutti frutti : 270
Adcal-D3 750mg/200unit caplets : 201
Calceos 500mg/400unit chewable tablets : 50
Calcichew D3 chewable tablets : 33
Colecalciferol 400unit capsules : 2
Colecalciferol 3,200unit capsules : 2
Accrete D3 One a Day 1000mg/880unit chewable tablets : 2
Calcichew D3 Forte chewable tablets : 2
Colecalciferol 2,000units/ml oral drops sugar free : 1
Colecalciferol 50,000unit tablets : 1
Hux D3 3,200unit capsules : 1
Aciferol D3 10,000unit tablets : 1
OsteoCaps D3 1,000unit capsules : 1
Colecalciferol 200unit / Calcium carbonate 1.25g chew tab : 9
Colecalciferol 400unit tablets : 9
Adcal-D3 Lemon chewable tablets : 9
Calci-D 1000mg/1,000unit chewable tablets : 9
Adcal-D3 Dissolve 1500mg/400unit effervescent tablets : 23
Colecalciferol 400unit / Calcium carbonate 1.5g efferv tab : 13
Aciferol D3 1,000unit tablets : 13
TheiCal-D3 1000mg/880unit chewable tablets : 17
Evacal D3 1500mg/400unit chewable tablets : 7
Fultium-D3 800unit capsules : 11
Colecalciferol 800unit capsules : 6
Colecalciferol 1,000unit tablets : 6
SunVit-D3 2,000unit tablets : 6
Hux D3 20,000unit capsules : 6
Colecalciferol 800unit/Calcium phosphate 3.1g oral pdr sach : 5
BabyD 1,000units/ml oral solution : 5
Stexerol-D3 1,000unit tablets : 5
Co-amilofruse (Amiloride hydrochloride/frusemide) 0 Potassium sparing diuretics and compounds 4 0.00 0.68 0.33 -2.07
Methylphenidate hydrochloride 8 CNS Stimulants and drugs used for ADHD 35 0.23 0.65 0.21 -2.05