Static outliers for Mercian PCN

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Mercian PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Asenapine 27 Drugs used for mania and hypomania 839 0.03 0.0 0.00 11.74
Phenazone/lidocaine 2 Otitis externa 1049 0.00 0.0 0.00 5.23
Other otitis external preparations 3 Otitis externa 1049 0.00 0.0 0.00 4.58
Methyl salicylate 177 Rubefacients, topical NSAIDS, capsaicin and poultice 5734 0.03 0.0 0.01 4.54
Bempedoic acid 13 Lipid-regulating drugs 54932 0.00 0.0 0.00 4.14

Prescribing where Mercian PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Tacrolimus 1 Corticosteroids and other immunosuppressants 56 0.02 0.61 0.28 -2.07
Famotidine 298 H2-Receptor antagonists 535 0.56 0.80 0.12 -1.96
Doxazosin mesilate 4556 Alpha-adrenoceptor blocking drugs 4697 0.97 0.99 0.01 -1.88
Oxycodone hydrochloride 347 Opioid analgesics 16981 0.02 0.08 0.03 -1.85
Oxycodone 5mg/5ml oral solution sugar free : 79
Oxycodone 5mg capsules : 1
Oxycodone 10mg modified-release tablets : 7
Oxycodone 20mg modified-release tablets : 11
Oxycodone 5mg modified-release tablets : 8
Oxycodone 10mg/1ml solution for injection ampoules : 20
Oxycodone 60mg modified-release tablets : 5
Oxycodone 30mg modified-release tablets : 3
Oxycodone 15mg modified-release tablets : 7
OxyNorm liquid 5mg/5ml oral solution : 16
OxyNorm 10mg capsules : 21
OxyContin 10mg modified-release tablets : 7
OxyContin 40mg modified-release tablets : 2
Longtec 5mg modified-release tablets : 17
Longtec 10mg modified-release tablets : 42
Longtec 20mg modified-release tablets : 22
Longtec 40mg modified-release tablets : 27
Longtec 30mg modified-release tablets : 6
Lynlor 5mg capsules : 6
Lynlor 10mg capsules : 2
Shortec 5mg capsules : 22
Shortec 10mg capsules : 8
Shortec 20mg capsules : 3
Shortec liquid 1mg/ml oral solution : 5
Mycophenolate mofetil 4 Antiproliferative immunosuppressants 394 0.01 0.19 0.10 -1.80