Static outliers for The Swan Network

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where The Swan Network is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Sodium benzoate 4 Mouth-washes, gargles and dentifrices 19 0.21 0.0 0.00 51.56
Testosterone propionate 1 Male sex hormones and antagonists 909 0.00 0.0 0.00 19.80
Gluten free/low protein drink 5 Foods for special diets 202 0.02 0.0 0.00 16.47
Low protein miscellaneous 5 Foods for special diets 202 0.02 0.0 0.00 14.20
Fluorescein sodium 8 Ocular diagnostic & peri-operative prepn & photodynamic tt 32 0.25 0.0 0.02 10.18

Prescribing where The Swan Network is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Chlorhexidine gluconate 15 Mouth-washes, gargles and dentifrices 19 0.79 0.98 0.05 -3.97
Procyclidine hydrochloride 29 Antimuscarinic drugs used in parkinsonism 62 0.47 0.85 0.11 -3.58
Carbimazole 81 Antithyroid drugs 101 0.80 0.93 0.04 -2.92
Doxycycline hyclate 290 Tetracyclines 742 0.39 0.63 0.09 -2.65
Combined ethinylestradiol 30mcg 595 Combined hormonal contraceptives 843 0.71 0.80 0.04 -2.39