Static outliers for Enfield Unity PCN

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Enfield Unity PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Tryptophan 31 Other antidepressant drugs 14318 0.00 0.00 0.00 7.51
Griseofulvin 33 Other antifungals 360 0.09 0.01 0.02 4.86
Gluten free/low protein grains/flours 19 Foods for special diets 891 0.02 0.00 0.00 3.93
Amiloride hydrochloride with loop diuretics 34 Potassium sparing diuretics and compounds 221 0.15 0.01 0.04 3.61
Gluten free/low protein pasta 47 Foods for special diets 891 0.05 0.01 0.01 3.59

Prescribing where Enfield Unity PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Terbinafine hydrochloride 327 Other antifungals 360 0.91 0.99 0.02 -4.86
Pregabalin 3511 Control of epilepsy 25745 0.14 0.27 0.06 -2.36
Filgrastim 0 Drugs used in neutropenia 2 0.00 0.85 0.36 -2.35
Morphine sulfate 1226 Opioid analgesics 11334 0.11 0.21 0.06 -1.87
Morphine sulfate 20mg/ml oral solution sugar free : 1
Morphine sulfate 10mg/1ml solution for injection ampoules : 67
Morphine 60mg modified-release tablets : 10
Morphine 10mg modified-release tablets : 70
Morphine 30mg modified-release tablets : 51
Morphine 10mg tablets : 30
Morphine 20mg tablets : 31
Morphine 15mg modified-release tablets : 45
Morphine 5mg modified-release tablets : 85
Morphine sulfate 10mg/5ml oral solution : 266
Morphine 30mg modified-release granules sachets sugar free : 4
Morphine 20mg modified-release granules sachets sugar free : 2
Morphine 10mg modified-release capsules : 29
Morphine 30mg modified-release capsules : 8
Morphine 60mg modified-release capsules : 6
Morphine sulfate 10mg/10ml solution for injection ampoules : 1
MST Continus 10mg tablets : 7
MST Continus 30mg tablets : 7
MST Continus 60mg tablets : 6
MST Continus 100mg tablets : 6
MST Continus suspension 20mg granules sachets : 4
MST Continus suspension 30mg granules sachets : 1
MST Continus 5mg tablets : 16
MST Continus 15mg tablets : 5
Oramorph 20mg/ml concentrated oral solution : 16
Oramorph 10mg/5ml oral solution : 275
Sevredol 10mg tablets : 26
Sevredol 20mg tablets : 4
Zomorph 10mg modified-release capsules : 107
Zomorph 30mg modified-release capsules : 31
Zomorph 60mg modified-release capsules : 3
Zomorph 100mg modified-release capsules : 6
Cyclizine hydrochloride 570 Drugs used in nausea and vertigo 6031 0.09 0.17 0.04 -1.66