Static outliers for Wakefield Health Alliance South PCN

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Wakefield Health Alliance South PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Hydrocortisone acetate 1 Corticosteroids 17 0.06 0.00 0.01 8.12
Empagliflozin/metformin 973 Other antidiabetic drugs 10433 0.09 0.00 0.01 7.91
Acetylcysteine 1085 Mucolytics 1918 0.57 0.02 0.07 7.26
Nedocromil sodium 1 Cromoglycate and related therapy 1 1.00 0.03 0.15 6.67
Povidone iodine 1 Ocular diagnostic & peri-operative prepn & photodynamic tt 29 0.03 0.00 0.01 6.61

Prescribing where Wakefield Health Alliance South PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Carbocisteine 814 Mucolytics 1918 0.42 0.97 0.08 -7.14
Sodium cromoglicate 0 Cromoglycate and related therapy 1 0.00 0.97 0.15 -6.67
Urea hydrogen peroxide 5 Removal of ear wax and other substances 21 0.24 0.83 0.26 -2.30
Cefalexin 196 Cephalosporins 227 0.86 0.96 0.06 -1.70
Estradiol 456 Oestrogens and Hormone Replacement Therapy 1390 0.33 0.48 0.09 -1.68
Estradiol 2mg tablets : 18
Estradiol 0.06% gel (750microgram per actuation) : 51
Estradiol 25micrograms/24hours transdermal patches : 1
Estradiol 1mg tablets : 40
Estradiol 40micrograms/24hours transdermal patches : 1
Estradiol 1mg gel sachets : 1
Estradiol 50micrograms/24hours transdermal patches : 7
Estraderm MX 25 patches : 22
Estraderm MX 50 patches : 10
Estraderm MX 100 patches : 2
Estraderm MX 75 patches : 3
Zumenon 2mg tablets : 10
Zumenon 1mg tablets : 15
Evorel 50 patches : 56
Evorel 25 patches : 29
Evorel 75 patches : 10
Evorel 100 patches : 3
Oestrogel Pump-Pack 0.06% gel : 48
FemSeven 50 patches : 1
Progynova TS 50micrograms/24hours transdermal patches : 1
Progynova TS 100micrograms/24hours transdermal patches : 8
Elleste Solo 1mg tablets : 32
Elleste Solo 2mg tablets : 11
Elleste Solo MX 40 transdermal patches : 22
Elleste Solo MX 80 transdermal patches : 5
Sandrena 500microgram gel sachets : 4
Sandrena 1mg gel sachets : 5
Estradot 75micrograms/24hours patches : 1
Estradot 100micrograms/24hours patches : 5
Estradot 25micrograms/24hours patches : 5
Estradot 37.5micrograms/24hours patches : 11
Estradot 50micrograms/24hours patches : 17
Lenzetto 1.53mg/dose transdermal spray : 1