Static outliers for Sevenoaks PCN

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where Sevenoaks PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Cocaine 6 Local anaesthetics 994 0.01 0.00 0.00 35.41
Azilsartan medoxomil 22 Angiotensin-II receptor antagonists 14644 0.00 0.00 0.00 8.16
Sodium fusidate 80 Antibacterial preparations also used systemically 572 0.14 0.02 0.03 4.24
Cyclizine lactate 141 Drugs used in nausea and vertigo 2242 0.06 0.01 0.01 4.05
Phenytoin 41 Control of epilepsy 13384 0.00 0.00 0.00 3.78

Prescribing where Sevenoaks PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Estradiol with progestogen 964 Oestrogens and Hormone Replacement Therapy 4390 0.22 0.38 0.07 -2.43
Estradiol 2mg / Norethisterone acetate 1mg tablets : 12
Estradiol 50microg/Norethist 170microg/24hours ptch : 27
Estradiol 1mg / Norethisterone acetate 500microgram tablets : 12
Estradiol 1mg / Dydrogesterone 5mg tablets : 7
Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets : 7
Estradiol valerate 2mg / Medroxyprogesterone 5mg tablets : 1
Estradiol 500micrograms / Dydrogesterone 2.5mg tablets : 4
Evorel Conti patches : 293
Evorel Sequi patches : 145
Kliofem tablets : 52
Femoston 2/10mg tablets : 52
Femoston 1/10mg tablets : 52
Femoston-conti 1mg/5mg tablets : 55
Femoston-conti 0.5mg/2.5mg tablets : 34
Elleste Duet 2mg tablets : 14
Elleste Duet 1mg tablets : 17
Elleste Duet Conti tablets : 12
Kliovance tablets : 127
Indivina 1mg/2.5mg tablets : 4
Indivina 1mg/5mg tablets : 3
Indivina 2mg/5mg tablets : 9
Novofem tablets : 17
FemSeven Conti patches : 8
Naproxen 2993 Non-steroidal anti-inflammatory drugs 5442 0.55 0.69 0.06 -2.23
Procyclidine hydrochloride 143 Antimuscarinic drugs used in parkinsonism 229 0.62 0.85 0.11 -2.12
Budesonide 16 Corticosteroids 48 0.33 0.72 0.18 -2.09
Oral rehydration salts 52 Oral sodium and water 236 0.22 0.62 0.20 -1.99