Static outliers for NHS East Sussex CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS East Sussex CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Levodopa 1 Dopaminergic drugs used in parkinsonism 22949 0.00 0.0 0.00 10.20
Pristinamycin 5 Some other antibacterials 802 0.01 0.0 0.00 6.84
Methylnaltrexone bromide 5 Peripheral opioid-receptor antagonists 78 0.06 0.0 0.01 6.61
Tolcapone 30 Dopaminergic drugs used in parkinsonism 22949 0.00 0.0 0.00 6.20
Meprobamate 4 Anxiolytics 35279 0.00 0.0 0.00 5.93

Prescribing where NHS East Sussex CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Entecavir 0 Chronic hepatitis B 1 0.00 0.94 0.19 -4.91
Cyclophosphamide 0 Alkylating drugs 1 0.00 0.95 0.21 -4.54
Naloxegol 68 Peripheral opioid-receptor antagonists 78 0.87 0.98 0.04 -2.94
Anagrelide hydrochloride 0 Drugs used in platelet disorders 5 0.00 0.85 0.33 -2.61
Beclometasone dipropionate 32469 Corticosteroids (respiratory) 86778 0.37 0.56 0.08 -2.32
Beclometasone 50micrograms/dose inhaler CFC free : 332
Beclometasone 100micrograms/dose inhaler CFC free : 922
Beclometasone 50micrograms/dose breath actuated inh CFC free : 3
Beclometasone 100mcg/dose breath actuated inhaler CFC free : 41
Beclometasone 200micrograms/dose dry powder inhaler : 14
Beclometasone 200micrograms/dose inhaler CFC free : 49
Beclometasone 250micrograms/dose inhaler CFC free : 11
Beclometasone 100microg/Formoterol 6microg/dose inh CFCfree : 369
Beclometasone 100microg/Formoterol 6microg/dose dry pdr inh : 124
Beclometasone 200microg/Formoterol 6microg/dose inh CFC free : 156
Beclometasone 200microg/Formoterol 6microg/dose dry pdr inh : 77
Qvar 50 inhaler : 1268
Qvar 100 inhaler : 2502
Qvar 50 Autohaler : 179
Qvar 100 Autohaler : 407
Qvar 50micrograms/dose Easi-Breathe inhaler : 73
Qvar 100micrograms/dose Easi-Breathe inhaler : 296
Easyhaler Beclometasone 200micrograms/dose dry pdr inhaler : 41
Clenil Modulite 50micrograms/dose inhaler : 2381
Clenil Modulite 100micrograms/dose inhaler : 10426
Clenil Modulite 200micrograms/dose inhaler : 2552
Clenil Modulite 250micrograms/dose inhaler : 242
Fostair 100micrograms/dose / 6micrograms/dose inhaler : 5923
Fostair 200micrograms/dose / 6micrograms/dose inhaler : 2737
Fostair NEXThaler 100microg/dose / 6microg/dose dry pdr inh : 837
Fostair NEXThaler 200microg/dose / 6microg/dose dry pdr inh : 331
Kelhale 50micrograms/dose inhaler : 18
Kelhale 100micrograms/dose inhaler : 48
Soprobec 50micrograms/dose inhaler : 13
Soprobec 200micrograms/dose inhaler : 13
Soprobec 100micrograms/dose inhaler : 79
Soprobec 250micrograms/dose inhaler : 5