Static outliers for NHS North Central London CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS North Central London CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Erythromycin 2 Antibacterials 8815 0.0 0.0 0.0 10.20
Hydrocortisone acetate 1 Corticosteroids 8392 0.0 0.0 0.0 10.20
Upadacitinib 1 Rheumatic disease suppressant drugs 19876 0.0 0.0 0.0 10.20
Other vitamin C (Ascorbic acid) preparations 1 Vitamin C (ascorbic acid) 775 0.0 0.0 0.0 8.35
Proguanil hydrochloride 1 Antimalarials 19286 0.0 0.0 0.0 7.68

Prescribing where NHS North Central London CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ascorbic acid 774 Vitamin C (ascorbic acid) 775 1.00 1.00 0.00 -8.35
Theophylline 2399 Theophylline 3752 0.64 0.86 0.08 -2.89
Filgrastim 0 Drugs used in neutropenia 2 0.00 0.87 0.31 -2.81
Terbinafine hydrochloride 3314 Other antifungals 3391 0.98 0.99 0.01 -2.71
Morphine sulfate 14358 Opioid analgesics 110885 0.13 0.22 0.04 -2.49
Morphine sulfate 1mg/1ml solution for injection ampoules : 3
Morphine sulfate 20mg/ml oral solution sugar free : 41
Morphine sulfate 10mg/1ml solution for injection ampoules : 494
Morphine sulfate 30mg/1ml solution for injection ampoules : 19
Morphine sulfate 20mg/1ml solution for injection ampoules : 6
Morphine 100mg modified-release tablets : 55
Morphine 60mg modified-release tablets : 234
Morphine 10mg modified-release tablets : 1118
Morphine 30mg modified-release tablets : 636
Morphine sulfate 60mg/2ml solution for injection ampoules : 6
Morphine 10mg tablets : 348
Morphine 20mg tablets : 174
Morphine 15mg modified-release tablets : 381
Morphine 5mg modified-release tablets : 796
Morphine sulfate 10mg/5ml oral solution : 4474
Morphine 30mg modified-release granules sachets sugar free : 29
Morphine 20mg modified-release granules sachets sugar free : 27
Morphine 60mg modified-release granules sachets sugar free : 5
Morphine 100mg modified-release granules sachets sugar free : 22
Morphine 50mg tablets : 14
Morphine 90mg modified-release capsules : 12
Morphine 120mg modified-release capsules : 11
Morphine 150mg modified-release capsules : 8
Morphine 100mg modified-release capsules : 48
Morphine 10mg modified-release capsules : 737
Morphine 30mg modified-release capsules : 424
Morphine 60mg modified-release capsules : 75
Morphine 200mg modified-release capsules : 22
Morphine sulfate 5mg/5ml solution for injection ampoules : 1
Morphine sulfate 10mg/10ml solution for injection ampoules : 5
MST Continus 10mg tablets : 213
MST Continus 30mg tablets : 149
MST Continus 60mg tablets : 114
MST Continus 100mg tablets : 54
MST Continus 200mg tablets : 17
MST Continus suspension 20mg granules sachets : 12
MST Continus suspension 30mg granules sachets : 1
MST Continus suspension 100mg granules sachets : 5
MST Continus 5mg tablets : 107
MST Continus 15mg tablets : 45
Oramorph 20mg/ml concentrated oral solution : 32
Oramorph 10mg/5ml oral solution : 2123
Sevredol 10mg tablets : 349
Sevredol 20mg tablets : 109
Sevredol 50mg tablets : 20
Zomorph 10mg modified-release capsules : 413
Zomorph 30mg modified-release capsules : 219
Zomorph 60mg modified-release capsules : 58
Zomorph 100mg modified-release capsules : 20
Zomorph 200mg modified-release capsules : 5
Morphgesic SR 10mg tablets : 24
Morphgesic SR 30mg tablets : 37
Morphgesic SR 60mg tablets : 1
Morphgesic SR 100mg tablets : 6