Static outliers for NHS Kent And Medway CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS Kent And Medway CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Minocycline hydrochloride 2 Oropharyngeal anti-infective drugs 1538 0.00 0.0 0.0 10.20
Everolimus 12 Other antineoplastic drugs 760 0.02 0.0 0.0 9.85
Tadalafil (Vasodilator Antihypertensive) 3 Vasodilator antihypertensive drugs 1806 0.00 0.0 0.0 9.63
Cocaine 6 Local anaesthetics 16299 0.00 0.0 0.0 7.76
Pyrimethamine 24 Antimalarials 35123 0.00 0.0 0.0 6.24

Prescribing where NHS Kent And Medway CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Other phosphate supplement preparations 125 Phosphate supplements 130 0.96 1.00 0.01 -2.45
Hydroxycarbamide 748 Other antineoplastic drugs 760 0.98 1.00 0.01 -1.69
Estradiol with progestogen 20932 Oestrogens and Hormone Replacement Therapy 66843 0.31 0.38 0.04 -1.52
Estradiol 2mg / Norethisterone acetate 1mg tablets : 369
Estradiol 50microg/Norethist 170microg/24hours ptch : 294
Estradiol 1mg / Norethisterone acetate 500microgram tablets : 454
Estradiol 1mg / Dydrogesterone 5mg tablets : 71
Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets : 76
Estradiol valerate 1mg / Medroxyprogesterone 5mg tablets : 24
Estradiol valerate 2mg / Medroxyprogesterone 5mg tablets : 25
Estradiol 50microg/Levonorgestrel 7microg/24hours ptch : 31
Estradiol 500micrograms / Dydrogesterone 2.5mg tablets : 69
Evorel Conti patches : 4954
Evorel Sequi patches : 2587
Kliofem tablets : 2149
Tridestra tablets : 40
Femoston 2/10mg tablets : 973
Femoston 1/10mg tablets : 1222
Femoston-conti 1mg/5mg tablets : 1462
Femoston-conti 0.5mg/2.5mg tablets : 870
Elleste Duet 2mg tablets : 281
Elleste Duet 1mg tablets : 713
Elleste Duet Conti tablets : 300
Kliovance tablets : 2787
Indivina 1mg/2.5mg tablets : 183
Indivina 1mg/5mg tablets : 56
Indivina 2mg/5mg tablets : 69
Novofem tablets : 549
FemSeven Sequi patches : 11
FemSeven Conti patches : 313
Methadone hydrochloride 24 Opioid dependence 231 0.10 0.51 0.28 -1.48
Beclometasone dipropionate 11413 Drugs used in nasal allergy 92064 0.12 0.24 0.08 -1.47