Static outliers for NHS South East London CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS South East London CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ziprasidone hydrochloride 2 Antipsychotic drugs 122487 0.0 0.0 0.0 10.20
Diamorphine hydrochloride 1 Cough suppressants 702 0.0 0.0 0.0 10.20
Caffeine citrate 2 CNS Stimulants and drugs used for ADHD 20349 0.0 0.0 0.0 9.82
Mefloquine hydrochloride 19 Antimalarials 21534 0.0 0.0 0.0 6.90
Cocaine 3 Local anaesthetics 9642 0.0 0.0 0.0 6.54

Prescribing where NHS South East London CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Atovaquone 0 Drugs for pneumocystis pneumonia 1 0.00 0.98 0.16 -6.17
Terbinafine hydrochloride 4229 Other antifungals 4327 0.98 0.99 0.01 -2.71
Potassium permanganate 95 Oxidisers and dyes 137 0.69 0.94 0.10 -2.37
Morphine sulfate 21152 Opioid analgesics 153236 0.14 0.22 0.04 -2.25
Morphine sulfate 20mg/ml oral solution sugar free : 5
Morphine sulfate 10mg/1ml solution for injection ampoules : 764
Morphine sulfate 30mg/1ml solution for injection ampoules : 26
Morphine sulfate 20mg/1ml solution for injection ampoules : 2
Morphine 100mg modified-release tablets : 62
Morphine 60mg modified-release tablets : 199
Morphine 10mg modified-release tablets : 2031
Morphine 30mg modified-release tablets : 894
Morphine sulfate 60mg/2ml solution for injection ampoules : 1
Morphine 10mg tablets : 827
Morphine 20mg tablets : 193
Morphine 15mg modified-release tablets : 537
Morphine 5mg modified-release tablets : 1176
Morphine sulfate 10mg/5ml oral solution : 5623
Morphine 30mg modified-release granules sachets sugar free : 14
Morphine 20mg modified-release granules sachets sugar free : 66
Morphine 60mg modified-release granules sachets sugar free : 9
Morphine 100mg modified-release granules sachets sugar free : 5
Morphine 50mg tablets : 16
Morphine 90mg modified-release capsules : 12
Morphine 120mg modified-release capsules : 1
Morphine 150mg modified-release capsules : 117
Morphine 100mg modified-release capsules : 12
Morphine 10mg modified-release capsules : 1244
Morphine 30mg modified-release capsules : 401
Morphine 60mg modified-release capsules : 126
Morphine 200mg modified-release capsules : 25
Morphine 0.2% in Intrasite gel : 21
Morphine sulfate 5mg/5ml solution for injection ampoules : 2
Morphine sulfate 10mg/10ml solution for injection ampoules : 6
MST Continus 10mg tablets : 462
MST Continus 30mg tablets : 220
MST Continus 60mg tablets : 108
MST Continus 100mg tablets : 11
MST Continus 200mg tablets : 6
MST Continus suspension 20mg granules sachets : 31
MST Continus suspension 30mg granules sachets : 7
MST Continus 5mg tablets : 203
MST Continus 15mg tablets : 162
Oramorph 20mg/ml concentrated oral solution : 16
Oramorph 10mg/5ml oral solution : 3565
Sevredol 10mg tablets : 508
Sevredol 20mg tablets : 223
Sevredol 50mg tablets : 27
MXL 30mg capsules : 7
MXL 200mg capsules : 10
Zomorph 10mg modified-release capsules : 606
Zomorph 30mg modified-release capsules : 415
Zomorph 60mg modified-release capsules : 76
Zomorph 100mg modified-release capsules : 10
Morphgesic SR 10mg tablets : 30
Morphgesic SR 30mg tablets : 24
Morphgesic SR 60mg tablets : 2
Morphgesic SR 100mg tablets : 6
Theophylline 1963 Theophylline 2837 0.69 0.86 0.08 -2.21