Static outliers for NHS Lincolnshire CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS Lincolnshire CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Aminosalicylic acid 1 Antituberculosis drugs 38 0.03 0.0 0.00 9.29
Erenumab 5 Treatment of acute migraine 24372 0.00 0.0 0.00 8.06
Sodium phenylbutyrate 5 Drugs used in metabolic disorders 55 0.09 0.0 0.01 6.57
Macrogol 4000 1 Osmotic laxatives 73961 0.00 0.0 0.00 3.81
Evolocumab 4 Lipid-regulating drugs 687975 0.00 0.0 0.00 3.73

Prescribing where NHS Lincolnshire CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Oseltamivir phosphate 0 Influenza 1 0.00 0.93 0.27 -3.47
Sertraline hydrochloride 131106 Selective serotonin re-uptake inhibitors 363004 0.36 0.45 0.04 -2.13
Mirtazapine 64836 Other antidepressant drugs 141898 0.46 0.56 0.05 -1.92
Ispaghula husk 7640 Bulk-forming laxatives 8305 0.92 0.96 0.03 -1.68
Nicotine 552 Nicotine dependence 2092 0.26 0.58 0.20 -1.56
Nicotine 7mg/24hours transdermal patches : 11
Nicotine 14mg/24hours transdermal patches : 6
Nicotine 21mg/24hours transdermal patches : 36
Nicotine 10mg/16hours transdermal patches : 20
Nicotine 15mg/16hours transdermal patches : 26
Nicotine 2mg lozenges sugar free : 9
Nicotine 4mg lozenges sugar free : 7
Nicotine 2mg medicated chewing gum sugar free : 5
Nicotine 4mg medicated chewing gum sugar free : 1
Nicotine 1.5mg lozenges sugar free : 8
Nicotine 25mg/16hours transdermal patches : 51
Nicotine 1mg/dose oromucosal spray sugar free : 25
Nicotine 15mg inhalation cartridges with device : 35
Nicorette Original 4mg medicated chewing gum : 6
Nicorette 500micrograms/dose nasal spray : 1
Nicorette Microtab 2mg sublingual tablets : 1
Nicorette Fruitfusion 2mg medicated chewing gum : 3
Nicorette Fruitfusion 4mg medicated chewing gum : 9
Nicorette invisi 10mg/16hours patches : 4
Nicorette invisi 15mg/16hours patches : 16
Nicorette invisi 25mg/16hours patches : 18
Nicorette Icy White 2mg medicated chewing gum : 8
Nicorette QuickMist 1mg/dose mouthspray freshmint : 37
Nicorette 15mg Inhalator : 15
Nicorette Cools 2mg lozenges : 3
Nicorette Cools 4mg lozenges : 2
Nicotinell TTS 10 patches : 11
Nicotinell TTS 20 patches : 9
Nicotinell TTS 30 patches : 16
NiQuitin 21mg patches : 32
NiQuitin 14mg patches : 18
NiQuitin 7mg patches : 16
NiQuitin Clear 21mg patches : 50
NiQuitin Clear 14mg patches : 14
NiQuitin Clear 7mg patches : 10
NiQuitin Mint 4mg lozenges : 4
NiQuitin Minis Mint 4mg lozenges : 3
NiQuitin Minis Mint 1.5mg lozenges : 6