Static outliers for NHS Berkshire West CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS Berkshire West CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Anakinra 5 Rheumatic disease suppressant drugs 19307 0.0 0.0 0.0 10.20
Phenylephrine hydrochloride and tropicamide 1 Mydriatics and cycloplegics 322 0.0 0.0 0.0 10.20
Boric acid 2 Vaginal and vulval infections 2240 0.0 0.0 0.0 8.57
Bambuterol hydrochloride 201 Selective beta(2)-agonists 65063 0.0 0.0 0.0 8.49
Sulfadiazine 8 Sulfonamides and trimethoprim 3990 0.0 0.0 0.0 6.26

Prescribing where NHS Berkshire West CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Zinc oxide 190 Soothing haemorrhoidal preparations 380 0.50 0.79 0.07 -4.14
Levothyroxine sodium 124849 Thyroid hormones 125387 1.00 1.00 0.00 -2.44
Isosorbide mononitrate 6038 Nitrates 9222 0.65 0.74 0.04 -2.21
Isosorbide mononitrate 10mg tablets : 1144
Isosorbide mononitrate 20mg tablets : 788
Isosorbide mononitrate 40mg tablets : 58
Isosorbide mononitrate 60mg modified-release tablets : 562
Isosorbide mononitrate 50mg modified-release capsules : 51
Isosorbide mononitrate 40mg modified-release tablets : 116
Isosorbide mononitrate 25mg modified-release capsules : 343
Isosorbide mononitrate 40mg modified-release capsules : 107
Isosorbide mononitrate 60mg modified-release capsules : 86
Isosorbide mononitrate 25mg modified-release tablets : 21
Isosorbide mononitrate 50mg modified-release tablets : 8
Elantan LA50 capsules : 13
Elantan LA25 capsules : 21
Ismo 10 tablets : 5
Imdur 60mg modified-release tablets : 89
Isib 60XL tablets : 6
Isodur 25XL capsules : 93
Isodur 50XL capsules : 19
Isotard 60XL tablets : 34
Isotard 40XL tablets : 157
Isotard 25XL tablets : 34
Isotard 50XL tablets : 3
Monomax XL 60mg tablets : 11
Chemydur 60XL tablets : 57
Zemon 40 XL tablets : 6
Carmil XL 60mg tablets (Milpharm) : 8
Xismox XL 60 tablets : 219
Trangina XL 60mg tablets : 23
Monomil XL 60mg tablets : 1935
Tardisc XL 60 tablets : 1
Nyzamac SR 40mg capsules : 3
Nyzamac SR 60mg capsules : 17
Doxycycline hyclate 6224 Tetracyclines 12068 0.52 0.64 0.06 -1.98
Clopidogrel 20298 Antiplatelet drugs 78027 0.26 0.33 0.03 -1.98