Static outliers for NHS Newcastle Gateshead CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS Newcastle Gateshead CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Nandrolone decanoate 3 Anabolic steroids 3 1.00 0.02 0.12 8.54
Imatinib mesilate 1 Other antineoplastic drugs 15 0.07 0.00 0.01 8.37
Tetracosactide 1 Hypothalamic & anterior pituitary hormone & antioestrogens 5 0.20 0.01 0.02 8.26
Benzocaine 8 Topical local anaesthetics and antipruritics 923 0.01 0.00 0.00 6.95
Penicillamine 239 Rheumatic disease suppressant drugs 16286 0.01 0.00 0.00 6.13

Prescribing where NHS Newcastle Gateshead CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Hydroxycarbamide 14 Other antineoplastic drugs 15 0.93 1.00 0.01 -7.87
Prasterone 0 Anabolic steroids 3 0.00 0.97 0.15 -6.48
Alginic acid compound preparations 16242 Compound Alginates and proprietary indigestion preparations 16485 0.99 1.00 0.00 -5.04
Alginate raft-forming oral suspension sugar free : 581
Sodium algin 500mg/Potassium bicarb 100mg/5ml susp SF : 689
Sodium algin 500mg/Potassium bicarb 100mg chew tab SF : 604
Gaviscon Original Aniseed Relief : 133
Gaviscon Infant oral powder sachets : 1272
Gaviscon Peppermint Liquid Relief : 81
Gaviscon Advance oral suspension aniseed (Reckitt Benckiser) : 893
Gaviscon Liquid 10ml sachets : 5
Gaviscon Advance Mint chewable tablets (Reckitt Benckiser) : 315
Gaviscon Double Action chewable tablets mint : 81
Gaviscon Double Action Liquid peppermint : 74
Gaviscon Peppermint chewable tablets : 44
Gaviscon Double Action Liquid aniseed : 24
Gaviscon Strawberry chewable tablets : 4
Gaviscon Advance oral susp peppermint (Reckitt Benckiser) : 1333
Gaviscon Double Action chewable tablets mixed berries : 4
Peptac liquid aniseed : 3694
Peptac liquid peppermint : 6405
Acidex oral suspension aniseed : 6
Co-codamol (Codeine phosphate/paracetamol) 11185 Non-opioid analgesics and compound preparations 180445 0.06 0.46 0.12 -3.43
Mesalazine (Systemic) 4507 Aminosalicylates 11657 0.39 0.62 0.07 -3.35
Mesalazine 400mg gastro-resistant tablets : 38
Mesalazine 500mg suppositories : 48
Mesalazine 1g/100ml enema : 10
Mesalazine 500mg modified-release tablets : 12
Mesalazine 1g suppositories : 209
Mesalazine 1g/application foam enema : 24
Mesalazine 2g/59ml enema : 49
Mesalazine 1.2g gastro-resistant modified-release tablets : 3
Mesalazine 800mg gastro-resistant tablets : 24
Mesalazine 1g gast res MR gran sachets sugar free : 4
Mesalazine 1g modified-release tablets : 7
Mesalazine 3g gast res MR gran sachets sugar free : 10
Mesalazine 1g gastro-resistant tablets : 4
Asacol 400mg MR gastro-resistant tablets : 221
Asacol 800mg MR gastro-resistant tablets : 185
Pentasa 500mg modified-release tablets : 298
Pentasa 1g suppositories : 65
Pentasa 1g modified-release granules sachets : 108
Pentasa 2g modified-release granules sachets : 133
Pentasa 1g modified-release tablets : 46
Pentasa 4g modified-release granules sachets : 5
Salofalk 250mg gastro-resistant tablets : 2
Salofalk 500mg suppositories : 5
Salofalk 2g/59ml enema : 33
Salofalk 1g/application foam enema : 20
Salofalk 1g gastro-resistant modified-release gran sachets : 64
Salofalk 500mg gast res MR gran sachets : 3
Salofalk 1.5g gastro-resistant modified-release gran sachets : 90
Salofalk 1g suppositories : 20
Salofalk 500mg gastro-resistant tablets : 13
Salofalk 3g gastro-resistant modified-release gran sachets : 56
Mezavant XL 1200mg tablets : 275
Octasa 800mg MR gastro-resistant tablets : 698
Octasa 400mg MR gastro-resistant tablets : 1713
Octasa 1600mg MR gastro-resistant tablets : 12