Static outliers for NHS Sheffield CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS Sheffield CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Tick-borne encephalitis vaccine 2 Vaccines and antisera 5749 0.00 0.00 0.00 8.88
Doravirine 2 HIV infection 16 0.12 0.00 0.01 8.37
Menthol 5 Lozenges and sprays 19 0.26 0.01 0.03 8.00
Clonazepam 9 Drugs used in status epilepticus 445 0.02 0.00 0.00 6.35
Dexamethasone sodium phosphate 23 Use of corticosteroids 27941 0.00 0.00 0.00 5.98

Prescribing where NHS Sheffield CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Sodium bicarbonate 1201 Oral bicarbonate 1205 1.00 1.00 0.00 -4.23
Insulin aspart 4675 Short-acting insulins 9427 0.50 0.78 0.08 -3.44
Morphine sulfate 12213 Opioid analgesics 98167 0.12 0.22 0.04 -2.63
Morphine sulfate 20mg/ml oral solution sugar free : 9
Morphine sulfate 10mg/1ml solution for injection ampoules : 548
Morphine sulfate 30mg/1ml solution for injection ampoules : 2
Morphine 100mg modified-release tablets : 5
Morphine 60mg modified-release tablets : 22
Morphine 10mg modified-release tablets : 251
Morphine 30mg modified-release tablets : 107
Morphine 10mg tablets : 121
Morphine 20mg tablets : 29
Morphine 15mg modified-release tablets : 29
Morphine 5mg modified-release tablets : 150
Morphine sulfate 10mg/5ml oral solution : 2496
Morphine 50mg tablets : 10
Morphine 10mg modified-release capsules : 164
Morphine 30mg modified-release capsules : 65
Morphine 60mg modified-release capsules : 8
Morphine 0.1% in Intrasite gel : 2
Morphine sulfate 10mg/10ml solution for injection ampoules : 5
MST Continus 10mg tablets : 367
MST Continus 30mg tablets : 182
MST Continus 60mg tablets : 102
MST Continus 100mg tablets : 17
MST Continus suspension 30mg granules sachets : 12
MST Continus 5mg tablets : 374
MST Continus 15mg tablets : 168
Oramorph 10mg/5ml oral solution : 3322
Sevredol 10mg tablets : 28
Sevredol 20mg tablets : 9
Zomorph 10mg modified-release capsules : 2106
Zomorph 30mg modified-release capsules : 1174
Zomorph 60mg modified-release capsules : 228
Zomorph 100mg modified-release capsules : 60
Morphgesic SR 10mg tablets : 21
Morphgesic SR 30mg tablets : 9
Morphgesic SR 60mg tablets : 2
Morphgesic SR 100mg tablets : 9
Venlafaxine 13500 Other antidepressant drugs 92393 0.15 0.26 0.05 -2.27
Venlafaxine 37.5mg tablets : 1449
Venlafaxine 75mg tablets : 1880
Venlafaxine 75mg modified-release capsules : 2593
Venlafaxine 150mg modified-release capsules : 2273
Venlafaxine 75mg modified-release tablets : 1269
Venlafaxine 150mg modified-release tablets : 1446
Venlafaxine 225mg modified-release tablets : 723
Venlafaxine 37.5mg modified-release tablets : 359
Venlafaxine 75mg/5ml oral solution : 8
Venlafaxine 37.5mg modified-release capsules : 618
Venlafaxine 225mg modified-release capsules : 238
Venlafaxine 300mg modified-release tablets : 61
Efexor XL 75mg capsules : 54
Efexor XL 150mg capsules : 48
Efexor XL 225mg capsules : 3
Vensir XL 75mg capsules : 107
Vensir XL 150mg capsules : 99
Vensir XL 225mg capsules : 15
ViePax XL 75mg tablets : 5
ViePax XL 150mg tablets : 6
ViePax 75mg tablets : 6
Venaxx XL 150mg capsules : 23
Venlalic XL 75mg tablets : 14
Venlalic XL 150mg tablets : 25
Venlalic XL 225mg tablets : 2
Venlalic XL 37.5mg tablets : 2
Venlablue XL 75mg capsules : 4
Venlablue XL 150mg capsules : 4
Venlablue XL 37.5mg capsules : 6
Depefex XL 75mg capsules : 74
Depefex XL 150mg capsules : 70
Vencarm XL 225mg capsules : 16
Cabergoline 241 Bromocriptine and other dopaminergic drugs 395 0.61 0.83 0.10 -2.24