Static outliers for NHS East Lancashire CCG

There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain. At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system using the BNF subparagraph as a denominator, for prescriptions dispensed between April 2021 and August 2021. We then calculate the mean and standard deviation for each numerator and denominator pair across all practices/CCGs/PCNs/STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given practice/CCG/PCN/STP is from the population mean. We then rank your “z-scores” to find the top 5 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not. Our full analytical method code is openly available on GitHub here.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at ebmdatalab@phc.ox.ac.uk. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

Prescribing where NHS East Lancashire CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Tetracaine 678 Local anaesthetics 4200 0.16 0.02 0.02 6.25
Disodium edetate 1 Ocular diagnostic & peri-operative prepn & photodynamic tt 157 0.01 0.00 0.00 4.70
Fosinopril sodium 74 Angiotensin-converting enzyme inhibitors 141391 0.00 0.00 0.00 4.40
Clemastine fumarate 18 Antihistamines 35405 0.00 0.00 0.00 4.04
Magnesium trisilicate 22 Antacids and simeticone 193 0.11 0.02 0.02 4.02

Prescribing where NHS East Lancashire CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Chlorhexidine gluconate 748 Chlorhexidine salts 749 1.00 1.00 0.00 -3.63
Lidocaine hydrochloride 3363 Local anaesthetics 4200 0.80 0.92 0.04 -3.27
Lidocaine 200mg/Adrenaline (base) 100microg/20ml inj vials : 170
Lidocaine 50mg/5ml (1%) solution for injection ampoules : 139
Lidocaine 40mg/2ml (2%) solution for injection ampoules : 210
Lidocaine 2% and Chlorhexidine gel : 1
Lidocaine 20mg/2ml (1%) solution for injection ampoules : 593
Lidocaine 100mg/10ml (1%) solution for injection ampoules : 33
Lidocaine 2.5% / Prilocaine 2.5% cream : 263
Lidocaine 100mg/5ml (2%) solution for injection ampoules : 76
Lidocaine 200mg/20ml (1%) solution for injection ampoules : 2
Lidocaine 44mg/Adrenaline (base) 27.5microg/2.2ml inj cart : 31
Lidocaine 5% medicated plasters : 677
Lidocaine 36mg/Adrenaline (base) 22.5microg/1.8ml inj cart : 1
Xylocaine 2% with Adrenaline 100microg/20ml inj vials : 257
Xylocaine 1% with Adrenaline 100microg/20ml inj vials : 37
Instillagel gel : 133
Emla 5% cream : 648
Lidocaine 50mg/5ml (1%) inj Mini-Plasco ampoules (Hameln) : 1
Versatis 700mg medicated plasters : 26
Lignospan Special 20mg/ml / 12.5micrograms/ml inj 2.2ml cart : 48
Lignospan Special 20mg/ml / 12.5micrograms/ml inj 1.8ml cart : 2
Bonjela Junior gel : 8
Ralvo 700mg medicated plasters : 7
Phenoxymethylpenicillin (Penicillin V) 4085 Benzylpenicillin and phenoxymethylpenicillin 4087 1.00 1.00 0.00 -3.10
Nicotine 57 Nicotine dependence 794 0.07 0.58 0.20 -2.52
Ulipristal acetate (Emergency Contraceptive) 18 Emergency contraception 98 0.18 0.39 0.09 -2.46